Reduces signs of skin fatigue and premature ageing by attacking the glycotoxins that build up when you don't get enough sleep. Directions of use: Use nightly for up to 28 days for best results. Can be used during the day. SPF should always be worn in the day. Use underneath a moisturiser. Optimum results use with NWEM but can also be used with NWAO. Product should last 6 -8 weeks with nightly use.