37 ACTIVES high performance anti-aging neck & décolletage treatment is a modern & innovative lotion targeting the visible signs of aging below the jaw line. In addition to the 37+ ingredients in the 37 EXTREME ACTIVES, Dr. Macrene has identified vital actives to target elasticity and reverse sun damage & aging, common to the delicate areas of the neck and chest.

Anti-Telomerase: Includes a red alga extract called Telosomyl®, which works to address the aging effects of telomerase, an enzyme responsible for clipping the ends of chromosomes culminating in senescence. Anti-telomerase therefore prevents this action and the cosmetic aging of the skin over time. Red Alga.

Anti-Glycation: An active area of research is the role of sugar molecules and how they contribute to the skin aging process by damaging tissue, a process called glycation. Among the identified anti-glycation compounds are resveratrol from red grapes and phenolic compounds from a number of plant antioxidants. Red Grape, Antioxidants.

Sun Damage Repair: Includes a number of repair agents for reversing the free radical attack on the skin from sun exposure. Such actives include watermelon extract, called Pepha-Protect® which is packed with ingredients that protect this fruit from the barrage of UV rays. Watermelon Extract.

DNA Repair: Incorporates DNA restore actives to reverse the changes caused by sun exposure, including tyrosine, proline and ATP. This DNA repair complex has been shown to decrease UV-induced mutations to the skin by 66%. Tyrosine, Proline, ATP.

Anti-Pollution: Polycyclic aromatic hydrocarbons (PAHs) are adsorbed onto the skin's surface in urban areas, which are then converted to quinones that cause the formation of free radicals that attack the skin. To guard against this are two forms of lipoencapsulated Vitamin C, Vitamin E and Ferulic Acid, and a host of plant-derived antioxidants that are included in our daily one step regimen. Lipoencapsulated Vitamin Cs, Vitamin E, Ferulic Acid, Antioxidants.

Firming: Palmitoyl hydroxyproline, also called Sepilift®, has been shown to address sagging to the skin of the neck and chest and to induce a firming activity.

Directions: Apply twice daily to neck and chest after cleansing.

The 37 ACTIVES line addresses the following areas:

• Anti-Wrinkle
• Anti-Brown Spot
• Anti-Redness
• Pro-Collagen
• Emollient/Moisturizers
• Barrier Fortification
• DNA Defense
• Antioxidants
• Cellular Restoration
• Aging Reversal